Peaks of transcription throughout the cell cycle are visualized for human (bar chart) and connections between 3 other species are shown if they share conserved genes that have the transcription peak at the corresponding time point.
The number of commonly highly expressed genes upon induction of different drugs is displayed through drug connections at every time point. Changes in the network of genes sharing drug phenotypes are also shown through time.
Phenotypic transitions of cell populations upon knockdown of cell cycle genes are visualized using arcs to connect phenotypes. The GO network dynamically highlights functions of the genes responsible for the transitions at one time point.
Visualizing peaks of transcription throughout the cell cycle and the corresponding cancer pathways that are pairwise enriched for the corresponding genes.
Phenotypic transitions of cells upon single perturbation events are visualized in 2D arc mode. Transparency of arcs can be modified for optimal display.
Heat maps and line plots of gene-associated values for each phenotype are interactive, highlighting gene and phenotype name upon hovering over with the mouse.
Arc mode displays connections between species that share conserved transcription events throughout the cell cycle.
Thresholds can be set for the phenotypes. Connections will be filtered correspondingly. Time offset can also be imposed.
Circular plots of phenotypic connections are drawn for every single time point.
The connections for one phenotype at a time can be analyzed.
Transitions to the polylobed phenotype highlight interesting trends.
The GO network highlights dynamically the enriched functionality of genes involved in connections at the particular time point.
Orthologous cell cycle events are connected between four species.
This is a demo showing the main functionality of the tool. Warning: may not display well in Chrome browser.